Table 2.

Haplotype tests of association showing ERAP2 C–C–G haplotype associated with preeclampsia.

Haplotypes	Haplotype frequency
	Control	PE	PEsuper	Eclampsia	HELLP
ERAP1
T–G	0.354	0.358	0.328	0.341	0.323
T–C	0.105	0.097	0.121	0.051	0.074
C–C	0.541	0.545	0.552	0.609	0.602
ERAP2
C–T–A	0.362	0.361	0.356	0.301	0.352
C–C–A	0.064	0.066	0.060	0.065	0.079
C–C–G	0.045	0.076a	0.050	0.045	0.065
T–C–G	0.488	0.482	0.515	0.523	0.452
LNPEP
T–C–A	0.123	0.130	0.105	0.132	0.135
C–T–G	0.398	0.376	0.375	0.345	0.397
T–C–G	0.479	0.494	0.520	0.521	0.468

ERAP1: rs30187–rs27044.

ERAP2: rs2549796–rs2927609–rs11135484.

LNPEP: rs27300–rs38034–rs2303138.

^aPE versus Control (Uncorrected p = 0.0013; p-value corrected for family-wise error rates by running 10,000 permutations: p = 0.0109).