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. 2020 Dec 17;8(1):219–231. doi: 10.1007/s40744-020-00263-y
Evaluating the impact of treatment in patients with Sjögren's syndrome is still challenging.
This is the first study showing how to evaluate treatment using ultrasonography of major salivary glands in primary Sjögren’s syndrome.
Pilocarpine improves salivary flow but does not change echostructural and vascularization of salivary glands in our pilot study. Unfortunately, a large number of patients were excluded due to poor treatment tolerance.
A larger population study and maybe another treatment is needed to evaluate echostructural and vascularization ultrasound changes in salivary glands.