Fig. 6.

Mechanical properties of cartilage of osteochondral explants on day 10. Mechanical properties of cartilage were determined after perturbation with IL-1β (n = 3), 65% MS (n = 19/21) or T3 (n = 19/23) using the fibril-network-reinforced biphasic model to calculate the a fibril network modulus, b Young’s modulus and c hydraulic permeability. Data are represented as mean ± SEM. P values of mean differences between controls and treated explants were estimated by generalized estimating equations (GEE) with robust variance estimators to account for donor effects. *P < 0.05, **P < 0.01