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. 2021 Mar 24;11:6798. doi: 10.1038/s41598-021-85487-w

Figure 3.

Figure 3

Frequencies of HIV genotypes that are either sensitive or resistant to vaccine induced immune responses, following introduction of a partially effective vaccine (here shown as years from vaccine rollout). The plot shows the mean and 95% credible interval of 64 replicates for each scenario (no vaccine, vaccine with risk compensation, and vaccine without risk compensation). The vaccine scenarios include a vaccine with 60% vaccine efficacy, 83.3% vaccine sensitive virus at vaccine rollout, and 70% population vaccine coverage (50% overall vaccine efficacy at rollout). Risk compensation is modeled as a 30% reduction in condom use among vaccinated individuals.