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. 2020 Sep 24;15(2):155–184. doi: 10.1007/s12079-020-00585-0

Table 2.

Prostanoid receptor synthetic agonists and antagonists

Receptor agonist reference antagonist reference
DP1 BW245C Rangachari et al. 1995 BWA868C Rangachari et al. 1995
TS-022 Arai et al. 2007 MK-0524 Chang et al. 2007
- - S-5751 Arimura et al. 2001
DP2 Indomethacin Hirai et al. 2002 Ramatroban Sugimoto et al. 2003
L-888,607 Gervais et al. 2005 - -
EP1 ONO-DI-004 Sugimoto and Narumiya 2007 ONO-8713 Sugimoto and Narumiya 2007
17-phenyl trinor PGE2 Dey et al. 2006 - -
EP2 ONO-AE1-259 Sugimoto and Narumiya 2007 PF-04418948 af Forselles et al. 2011
butaprost Kashmiry et al. 2018 - -
EP3 ONO-AE-248 Norel et al. 2004 enprostil Abramovitz et al. 2000
SC-46275 Savage et al. 1993 M&B 28767 Abramovitz et al. 2000
MB28767 Kotani et ai. 2000 - -
Sulprostone Jin et al. 1997, Abramovitz et al. 2000 - -
EP4 ONO-AE1-329 Sugimoto and Narumiya 2007 ONO-AE3-208 Sugimoto and Narumiya 2007
tetrazolo PGE1 Jones et al. 2009 CJ-042794 Jones et al. 2009
IP Cicaprost Jones et al. 2009 RO-1138452 Jones et al. 2009
Carbacyclin Jones et al. 2009 RO-3244794 Jones et al. 2009
iloprost Jones et al. 2009 - -
19(S)-HETE Tunaru et al. 2016 - -
TP U-46619 Abramovitz et al. 2000 AH-23848 Jones et al. 2009
STA2 Hirata et al. 1996 Ramatroban Jones et al. 2009
I-BOP Hirata et al. 1996 Vapiprost Jones et al. 2009
- - SQ29548 Wright et al. 1998
- - S-145 Ushikubi et al. 1989b
FP Fluprostenol Sharif et al. 2000b OBE022 Pohl et al. 2018
Cloprostenol Anderson et al. 1999 THG113 Peri et al. 2002
Latanoptost Abramovitz et al. 2000 AS604872 Jones et al. 2009