Figure 6.
Effects of dietary modification on structural injury following IRI surgery. (A,B) Hematoxylin and eosin staining of post-ischemic kidneys on day 2 after IRI. Arrows indicate damaged or necrotic tubules (×200). (C) The percentages of necrotic tubules tended to be higher in the mice fed an HF or HS diet compared to the control group. The HF+HS diet group fed for 1 week showed a significantly higher percentage of necrotic tubules than the control group. *P < 0.05, compared with the control group (n = 5–10 for each group). Statistical analysis was performed using the Mann-Whitney U-test. HF, high-fat; HS, high-salt; HF + HS, high-fat with high-salt.