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. 2021 Mar 11;15:573858. doi: 10.3389/fnins.2021.573858

FIGURE 4.

FIGURE 4

Intergroup differences in internetwork FC between the tinnitus patients and HCs and between the patients before and after sound therapy. (A) Compared with the HCs, the tinnitus patients exhibited a decreased (i.e., positive) (mVN and lVN) or an increased (i.e., less negative) (mVN and SMN; mVN and AN) internetwork FC at baseline. (B) Compared with HCs, tinnitus patients showed a decreased (i.e., positive) (AN and pDMN; DAN and LFPN) internetwork FC after sound therapy. (C) Compared with the patients at baseline, the tinnitus patients exhibited increased (i.e., negative) (LFPN and pDMN; LFPN and RFPN; aDMN and AN; aDMN and DAN) internetwork FC after sound therapy. AN, auditory network; aDMN, anterior default mode network; pDMN, posterior default mode network; LFPN, left frontoparietal network; RFPN, right frontoparietal network; lVN, lateral visual network; mVN, medial visual network; SMN, sensorimotor network; DAN, dorsal attention network; FC, functional connectivity, HC, healthy control. The red line represents positive FC; the green line represents negative FC.