TABLE 2.

Difference in gray/white matter volume between the tinnitus patients and healthy controls and between patients before and after sound therapy.

Anatomical region	MNI coordinate			Voxel	Peak
				size	T-value
	x	y	z
Gray matter (FWE cluster p < 0.05)
Gray matter volume (baseline)
Tinnitus patients < Healthy controls
Left middle temporal gyrus	−65	−3	−24	690	5.06
Gray matter volume (after treatment)
Tinnitus patients < Healthy controls
Left middle temporal gyrus	−65	−3	−23	831	5.18
White matter
White matter volume (baseline)
Tinnitus patients < Healthy controls
Left middle temporal gyrus (FWE cluster p < 0.05)	−60	2	−29	373	5.39
White matter volume (after treatment)
Tinnitus patients < Healthy controls
Left middle temporal gyrus (uncorrected)	−60	2	−29	362	5.49
White matter volume (FWE cluster P < 0.05)
Tinnitus patients (baseline) < Tinnitus patients (after treatment)
Cingulum_Mid_L (aal)	−8	−27	39	110	8.40
Calcarine_R (aal)	24	−51	15	65	7.98
Cingulum_Mid_R (aal)	8	−30	44	115	6.50
Rolandic_Oper_L (aal)	−45	−6	15	113	6.06
Left parietal and frontal lobe	−29	−41	44	1,345	8.04

MNI, Montreal Neurological Institute; FWE, family wise error; L, left; R, right.