Table 1.
Clinicopathological factors | Overall survival | Progression-free survival | ||||
---|---|---|---|---|---|---|
N | Hazard ratio | P-value | N | Hazard ratio | P-value | |
Sex | ||||||
Female | 118 | 2.53(1.37–4.67) | 0.0023 | 120 | 2.11(1.24–3.59) | 0.0047 |
Male | 246 | 1.82(1.16–2.84) | 0.0081 | 246 | 0.8(0.55–1.16) | 0.2297 |
Stage | ||||||
1 | 170 | 1.79(0.97–3.31) | 0.0589 | 170 | 1.58(0.93–2.7) | 0.0872 |
2 | 83 | 7.99(1.08–59.09) | 0.0155 | 84 | 0.57(0.31–1.03) | 0.0577 |
1+2 | 253 | 1.75(1.02–3.01) | 0.0392 | 254 | 1.21(0.79–1.85) | 0.3853 |
3 | 83 | 3.15(1.46–6.77) | 0.002 | 83 | 1.62(0.94–2.78) | 0.0768 |
2+3 | 166 | 2.88(1.6–5.2) | 0.0002 | 167 | 1.22(0.82–1.82) | 0.3209 |
4 | 4 | 5 | ||||
3+4 | 87 | 2.47(1.32-4.61) | 0.0035 | 88 | 1.67(0.97–2.86) | 0.0599 |
Grade | ||||||
1 | 55 | 3.25(1.25–8.47) | 0.0109 | 55 | 1.56(0.65–3.74) | 0.3133 |
2 | 174 | 2.52(1.38–4.62) | 0.0019 | 175 | 1.56(0.97–2.5) | 0.0618 |
3 | 118 | 1.82(0.93–3.56) | 0.0751 | 119 | 0.69(0.38–1.23) | 0.2081 |
4 | 12 | 12 | ||||
AJCC_T | ||||||
1 | 180 | 1.7(0.95–3.07) | 0.0728 | 180 | 1.55(0.94–2.58) | 0.0854 |
2 | 90 | 4.76(1.13–20.07) | 0.0188 | 92 | 0.66(0.38–1.14) | 0.13 |
3 | 78 | 2.55(1.18–5.51) | 0.0136 | 78 | 1.48(0.83–2.65) | 0.1858 |
4 | 13 | 13 | ||||
Vascular invasion | ||||||
micro | 90 | 2.32(1.09–4.95) | 0.0255 | 91 | 0.67(0.38–1.19) | 0.168 |
macro | 16 | 16 | ||||
None | 204 | 1.5(0.87–2.58) | 0.1375 | 204 | 1.32(0.83–2.08) | 0.2384 |
Race | ||||||
White | 181 | 1.66(1.03–2.66) | 0.0355 | 183 | 1.48(0.97–2.26) | 0.0685 |
Asian | 155 | 2.74(1.41–5.33) | 0.0019 | 155 | 1.82(0.97–3.39) | 0.0566 |
Black or African American | 17 | 17 | ||||
Sorafenib treatment | ||||||
Treated | 29 | 4.18(0.9–19.36) | 0.0484 | 30 | 1.99(0.88–4.48) | 0.092 |
Alcohol consumption | ||||||
yes | 115 | 2.54(1.11–5.79) | 0.0221 | 115 | 1.26(0.71–2.23) | 0.4359 |
none | 202 | 1.9(1.12–3.23) | 0.0162 | 204 | 1.25(0.82–1.91) | 0.3003 |
Virus hepatitis | ||||||
Yes | 150 | 2.13(1.08–4.18) | 0.0255 | 152 | 0.67(0.4–1.12) | 0.121 |
None | 167 | 2.06(1.3–3.26) | 0.0017 | 167 | 1.68(1.06–2.65) | 0.0251 |
The meaning of the bold values is P-value < 0.05.