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. 2021 Mar 11;15:657361. doi: 10.3389/fnins.2021.657361

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Copyright © 2021 Bian, Guo, Jiang, Chen, Liu, Zheng and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Frequency spectrum analysis on GCaMP6f responses from colorectal afferents evoked by mechanical colorectal distension and mucosal shearing. (A) The implemented mechanical colorectal distension and luminal shear flow, respectively. (B) Evoked GCaMP6f signals in individual DRG neurons. (C) The frequency domain of the GCaMP6f transients from fast Fourier transform. (D) Band-pass filtered GCaMP6f signals.