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. 2021 Mar 11;12:609992. doi: 10.3389/fphar.2021.609992

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Copyright © 2021 Wang, Zhang, Li, Zhang, Guo, Chang, Chen, Wang, Wang, Song, Zhao and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Experimental protocol and phytochemical analysis. (A) Animal experiment design. (B) HPLC chromatogram of SND recorded at 254 nm. Peaks of four primary ingredients, including (1)Quercetin, (2)Ammonium glycyrrhizate, (3)6-Gingerol, and (4)Carbenoxolone, are shown. (C) Structures of the four active ingredients.