Table 3.
Clinical outcomes in patients with haemophilia and HCV exposure by HCV status
| Total (n = 73) |
Spontaneous clearance (n = 26) | Chronic infection (n = 46) |
p value | |
|---|---|---|---|---|
| Liver cirrhosis | 16 (21.9) | 0 (0.00) | 16 (34.8) | 0.001 |
| Hepatocellular carcinoma | 2 (2.74) | 0 (0.00) | 2 (4.35) | 0.532 |
| Liver transplant | 3 (4.11) | 0 (0.00) | 3 (6.52) | 0.183 |
| Death, overall* | 17 (23.3) | 7 (26.9) | 9 (19.6) | 0.553 |
| Liver-related | 4 (5.48) | 0 (0.00) | 4 (8.70) | − |
| Variceal haemorrhage | 2 (2.74) | − | 2 (4.35) | − |
| Hepatocellular carcinoma | 1 (1.37) | − | 1 (2.17) | − |
| Sepsis | 1 (1.37) | − | 1 (2.17) | − |
| Haemophilia-related | 7 (9.59) | 4 (15.4) | 3 (6.52) | − |
| Acquired immunodeficiency virus | 2 (2.74) | 1 (3.85) | 1 (2.17) | − |
| Not reported | 4 (5.48) | 3 (11.5) | 1 (2.17) | − |
| Age at death, years | 48.4±15.4 | 50.2±14.4 | 47.4±17.0 | 0.758 |
Data are presented as n (%) or mean ± SD.
*
One patient: missing information. HCV, hepatitis C virus.