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. 2021 Mar 24;11:6751. doi: 10.1038/s41598-021-86147-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gene expression profiles and secretion properties of BMSCs and CBMSCs cultured on BCP biomaterial. (A) Histogram showing optical density (OD) at 570 nm as Mean ± standard deviation (SD). (B) Histogram showing gene expression of BMSCs and CBMSCs as Mean ± standard error of the mean (SEM) and normalized to BMSCs. (C) Histogram showing ALP activity as Mean ± SD and normalized to BMSCs. (D) Histogram showing levels of secreted interleukin (IL)-8 and IL-6 as Mean ± SD and normalized to BMSCs. Statistical analysis was by unpaired Student’s t-test. *Significant difference between MSCs of different tissue origin.