Table 4.

Correlation between TLR2, TLR4, and TLR9 SNPs and risk of typical or severe TM.

Gene	SNP ID	Typical cases vs matched controls				Severe cases vs matched controls				Typical cases vs severe cases
		Genotype		Allele		Genotype		Allele		Genotype		Allele
		χ² value	P value	χ² value	P value	χ² value	P value	χ² value	P value	χ² value	P value	χ² value	P value
TLR2	rs11935252	1.29	0.52	0.91	0.34	1.20	0.57	1.07	0.30	0.78	0.68	0.49	0.49
	rs11938228	2.05	0.36	2.04	0.15	1.92	0.38	1.66	0.20	2.15	0.34	1.43	0.23
	rs1339	6.76	0.03	6.91	0.01	1.22	0.54	0.61	0.43	2.00	0.37	1.54	0.22
	rs3804099	0.97	0.62	0.24	0.62	0.34	0.84	0.31	0.58	0.99	0.61	0.06	0.81
	rs76112010	4.66	0.10	4.66	0.10	5.46	0.07	5.46	0.07	3.15	0.21	1.84	0.18
	rs7656411	3.47	0.18	2.24	0.13	8.39	0.02	0.77	0.38	3.12	0.21	1.04	0.31
TLR4	rs11536878	0.34	0.84	0.08	0.78	1.16	0.56	0.00	1.00	1.01	0.60	0.08	0.78
	rs11536889	2.51	0.29	1.81	0.18	0.78	0.68	0.25	0.62	1.64	0.44	1.44	0.23
	rs11536891	0.64	0.73	0.61	0.45	0.48	0.82	0.37	0.54	0.51	0.78	0.41	0.52
	rs1554973	0.38	0.86	0.26	0.61	3.01	0.24	1.16	0.28	0.64	0.73	0.21	0.65
	rs1927911	0.59	0.74	0.31	0.58	1.13	0.57	0.46	0.50	1.13	0.74	0.75	0.39
	rs7856729	0.64	0.73	0.61	0.44	0.82	0.67	0.64	0.42	0.95	0.62	0.75	0.39
TLR9	rs187084	3.20	0.20	2.63	0.11	0.15	0.93	0.00	1.00	3.39	0.18	1.24	0.27
	rs352140	2.42	0.30	2.11	0.30	0.28	0.87	0.28	0.60	2.50	0.29	0.69	0.41

Typical cases, AIDS patients with typical talaromycosis; Severe cases, AIDS patients with severe talaromycosis; TLR, Toll-like receptor; SNP, single nucleotide polymorphism.

In bold: P value less than 0.05 and is regarded as statistically significant.