Table 2.
Comparison of rectal G1 NET with G2 tumor (n = 601).
| G1 | G2 | p | ||
|---|---|---|---|---|
| Gender | male | 292 | 54 | 0.290 |
| female | 223 | 32 | ||
| Age | mean | 49 | 52 | 0.043 |
| Distance from anal verge (cm) | mean | 5.9 | 5.8 | 0.768 |
| Tumor size (cm) | mean | 0.8 | 2.2 | 3.3E-10 |
| Invading depth* | T0 | 394 | 5 | 4.5E-47 |
| T1 | 83 | 31 | ||
| T2 | 22 | 12 | ||
| T3 | 6 | 25 | ||
| T4 | 10 | 11 | ||
| T0-1/total, % | 92.6 | 42.8 | ||
| N stage | N0 | 488 | 48 | 5.0E-27 |
| N1 | 27 | 38 | ||
| N1/total, % | 5.2 | 44.2 | ||
| M stage | M0 | 504 | 59 | 5.6E-25 |
| M1 | 11 | 27 | ||
| M1/total, % | 2.1 | 31.4 | ||
| TNM stage** | Ia | 376 | 16 | 3.2E-39 |
| Ib | 93 | 15 | ||
| II | 15 | 6 | ||
| III | 20 | 22 | ||
| IV | 11 | 27 | ||
| I/total, % | 91.1 | 36.0 | ||
| Microvascular invasion*** | no | 244 | 49 | 1.0E-4 |
| yes | 9 | 10 | ||
| yes/total | 3.6 | 16.9 | ||
| Perineural invasion*** | no | 244 | 44 | 2.9E-10 |
| yes | 5 | 14 | ||
| yes/total, % | 2.0 | 24.1 | ||
| Surgical modality**** | EMR | 48 | 1 | 1.6E-27 |
| ESD | 179 | 17 | ||
| TEM | 246 | 20 | ||
| AR/APR/hartman | 36 | 41 | ||
| local excision/total, % | 92.9 | 48.1 |
EMR, Endoscopic Mucosal Resection; ESD, Endoscopic Submucosal Dissection; TEM, Transanal Endoscopic Microsurgery; AR, Anterior Resection; APR, Abdomen Perineal Resection.
*T stage only indicates tumor invading depth without consideration of tumor diameter.
**TNM stage is according to ENETS TNM staging system, in which T stage is determined by combination of invading depth and tumor size.
***Information about microvascular invasion and perineural invasion is lost for 48.1% and 48.9% of cases.
****Local excision includes the sum of EMR, ESD, and TEM.