TABLE 1.

Overview of potassium channels with roles in the cell death and survival of upper gastrointestinal tract cancers.

Channels	Organ	Mechanism/pathway	Induction	References
KCNA5	GC		Aminopyridine, tetraethylammonium	Han et al., 2007
HERG	GC		Cisapride	Shao et al., 2005
	GC		siRNA technology	Shao et al., 2008
	GC		siRNA technology	Zhang et al., 2012
HERG1	ESCC	TXNDC5, PI3K/AKT pathway	shRNA technology	Wang et al., 2019
KCNT2	GC	HAND2-AS1, miR-590-3p	overexpression vector	Yu et al., 2020
KCNK9	GC		siRNA technology	Cikutović-Molina et al., 2019
KCNMA1	GC	PTK2	Overexpression plasmid	Ma et al., 2017

ESCC, esophageal squamous cell carcinoma; GC, gastric cancer.