Table 5.
Performance of CPIS, CPIS-mic, CPIS-cult, SPIS, SPIS-mic, and SPIS-cult at inclusion for diagnosis of VAP (mini-BAL culture confirmed)
| Parameters | Sensitivity% | Specificity% | PPV% | NPV% | LR+ | LR- |
|---|---|---|---|---|---|---|
| CPIS ≥ 6 | 57.5 (45.9–68.5) | 60 (40.6–77.3) | 79.3 (66.6–88.8) | 34.6 (21.9–49.1) | 1.43 (0.89–2.32) | 0.71 (0.48–1.04) |
| CIPS mic ≥ 6 | 71.3 (60.1–80.8) | 60 (40.6–77.3) | 82.6 (71.7–90.7) | 43.9 (28.5–60.3) | 1.70 (1.1–2.8) | 0.48 (0.3–0.8) |
| CPIS cult ≥ 6 | 78.8 (68.2–87.1) | 63.3 (43.9–80.1) | 85.1 (74.9–92.3) | 53 (35.5–69.6) | 2.15 (1.3–3.5) | 0.34 (0.2–0.6) |
| SPIS ≥ 6 | 46.3 (35–57.8) | 73.3 (54.1–87.7) | 82.2 (67.9–92) | 33.9 (22.6–46.7) | 1.37 (0.9–3.3) | 0.73 (0.5–0.9) |
| SPIS mic ≥ 6 | 77.5 (66.8–86.1) | 76.7 (57.7–90.1) | 89.9 (80.2–95.8) | 56.1 (39.8–71.5) | 3.32 (1.7–6.4) | 0.3 (0.2–0.5) |
| SPIS cult ≥ 6 | 87.5 (78.2–93.8) | 76.7 (57.7–90.1) | 90.9 (82.2–96.3) | 69.7 (51.3–84.4) | 3.8 (1.9–7.2) | 0.2 (0.1–0.3) |
Notes: Data are presented as % (95% CI). CPIS, clinical pulmonary infection score; LR+, positive likelihood ratio, LR−, negative likelihood ratio; LUS, lung ultrasound; NPV, negative predictive value; PPV, positive predictive value; SPIS, sono-pulmonary infection score