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. 2021 Mar 11;9:640972. doi: 10.3389/fcell.2021.640972

TABLE 3.

Minimal mitostatic concentrations of drugs (in nM), causing significant mitotic delay or blockade.

Cell line Nocodazole Taxol Vinorelbine
3T3 300 nM 100 nM 10 nM
A549 100 nM 300 nM 300 nM
HaCaT 100 nM 30 nM 10 nM
HPF 100 nM 10 nM 30 nM
HT1080 300 nM 100 nM 100 nM
MCF-7 100 nM 30 nM ≤ 10 nM
PC-3 100 nM 30 nM ≤ 10 nM
U2OS 100 nM 30 nM 300 nM
HeLa 100 nM 10 nM 100 nM

For each cell culture, at least 50 mitoses were analyzed at minimal mitostatic concentration.