Figure 3.
Copy number profiles of GEP-NEC organoids. (A) Copy number profiles of GEP-NEC organoids are generated based on low-coverage whole genome sequencing and represented on a log2 scale. NEC-01013: passage (P) 11; NEC-02002: P5. (B) Copy number profiles were based on SNPs identified by whole exome sequencing and analyzed by Sequenza. Allele frequencies are given as ratios and used to infer copy number. NEC-01013: P11; NEC-02002: P15.