Table 1.

Expression of Ki-67 and neuroendocrine markers in original tumor and organoids¹.

	Synaptophysin		Chromogranin A		Ki-67
	Original tumor	Organoids	Original tumor	Organoids	Original tumor	Organoids
NEC-01010 (P7)2	50%3	0%	0%	0%	70%	90%
NEC-01013 (P20)	80%	100%	0%	0%	100%	90%
NEC-02002 (P15)	100%	100%	0%	0%	40%	60%
NEC-02006 (P8)	80%	0%	20%	0%	N/A	90%
NEC-02007 (P3)	100%	50%	80%	60%	70%	70%

¹Values indicate percentage of cells positive for the marker.

²P7 indicates organoids were stained at passage 7.

³NEC-01010 showed heterogeneous expression of synaptophysin, with some areas being completely negative, and some areas 100% positive.