Table 3.
MUC1 and MUC5AC mRNA expression profiles based on the clinicopathological criteria of patients.
| Clinicopathological criteria | MUC1 mRNA | MUC5AC mRNA | ||||
|---|---|---|---|---|---|---|
| Positiven = 96 | Negativen = 106 | P-value | Positiven = 40 | Negative | P-value | |
| Age (years) | n = 172 | |||||
| ≥60 (n = 120) | 53 | 67 | 0.248 | 22 | 98 | 0.526 |
| <60 (n = 82) | 43 | 39 | 18 | 64 | ||
| Sex | ||||||
| Male (n = 110) | 56 | 54 | 0.292 | 24 | 86 | 0.432 |
| Female (n = 92) | 40 | 52 | 16 | 76 | ||
| Tumor location | ||||||
| Right colon (n = 48) | 18 | 30 | 0.111 | 14 | 34 | 0.062 |
| Left colon (n = 154) | 78 | 76 | 26 | 128 | ||
| Histological type | ||||||
| NMC (n = 120) | 53 | 67 | 0.487 | 23 | 97 | 0.552 |
| MA (n = 54) | 29 | 25 | 13 | 41 | ||
| MC (n = 28) | 14 | 14 | 4 | 24 | ||
| Differentiation | ||||||
| Well (n = 164) | 81 | 83 | 34 | 130 | 0.602 | |
| Moderate (n = 30) | 13 | 17 | 0.356 | 4 | 26 | |
| Poor (n = 8) | 2 | 6 | 2 | 6 | ||
| Stages | ||||||
| I (n = 20) | 5 | 15 | 0.016 | 3 | 17 | 0.501 |
| II (n = 80) | 32 | 48 | 20 | 60 | ||
| III (n = 92) | 53 | 39 | 15 | 77 | ||
| IV (n = 10) | 6 | 4 | 2 | 8 | ||
| Lymph node metastasis | ||||||
| N0 (n = 104) | 37 | 67 | 0.002 | 23 | 81 | 0.516 |
| N1 (n = 62) | 39 | 23 | 13 | 49 | ||
| N2 (n = 34) °) | 18 | 16 | 4 | 30 | ||
| N3 (n = 2) | 2 | 0 | 0 | 2 | ||
| IHC profile | 0.000 | 0.000 | ||||
| Positive | 88 | 0 | 30 | 0 | ||
| Negative | 8 | 106 | 10 | 162 | ||
IHC: Immunohistochemistry.