Table 5.
Multiple regression analysis between pulmonary function and vascular endothelial function parameters in diabetes group.
| Dependent variable | Coefficient | P value | ||||
|---|---|---|---|---|---|---|
| R | F | NO | ET-1 | FMD | ||
| VC | 0.865 | 156.215 | 7.641 | - 3.900 | 0.126 | 0.006* |
| FVC | 0.822 | 109.365 | 1.992 | - 6.467 | 2.282 | <0.0001* |
| FEV1 | 0.730 | 60.213 | 2.024 | - 4.699 | 1.248 | <0.0001* |
| PEF | 0.833 | 119.603 | 5.006 | - 5.053 | 1.506 | 0.002* |
| MVV | 0.818 | 106.415 | 1.177 | - 6.065 | 3.507 | 0.001* |
| TLC | 0.808 | 199.913 | 3.993 | - 4.189 | 2.574 | <0.0001* |
| FEV1/FVC | 0.779 | 81.387 | 0.618 | - 6.625 | 1.650 | <0.0001* |
| DLCO | 0.843 | 129.367 | 6.125 | - 3.833 | 2.445 | 0.020* |
| DLCO/VA | 0.379 | 398.745 | 3.618 | - 2.181 | 0.370 | 0.080 |
*P< 0.05, Statistically significant.
FMD, flow-mediated dilation; NO, nitric oxide; ET-1, endothelin-1; VC, vital capacity; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; PEF, peak expiratory force; MVV, maximal voluntary ventilation; TLC, total lung capacity; FEV1/FVC, forced expiratory volume in 1 second/forced vital capacity; DLCO, diffusing capacity for carbon monoxide of lung; DLCO/VA, diffusing capacity for carbon monoxide of lung/unit volume.