Table 3.
Effect of juvenile R treatment on adult serum biochemical markers and on body, testis, and epididymal weight and relative testis and epididymal weight.
| Control | R 50 mg/kg/day | |
|---|---|---|
| Urea (mg/dl) | 46.4 ± 3.3 | 49.2 ± 8 |
| Creatinine (mg/dl) | 0.30 ± 0.09 | 0.29 ± 0.05 |
| AST (UI/l) | 99.4 ± 17.5 | 87.9 ± 28.1 |
| ALT (UI/l) | 33.8 ± 3.4 | 29.9 ± 2.2 |
| Body Weight | 577.3 ± 54.6 | 596.7 ± 18.0 |
| Testis Weight | 1.9 ± 0.2 | 1.8 ± 0.3 |
| TW/BW Ratio (%) | 0.36 ± 0.03 | 0.34 ± 0.02 |
| Epididymal Weight (g) | 0.94 ± 0.30 | 0.85 ± 0.30 |
| EW/BW Ratio (%) | 0.16 ± 0.05 | 0.14 ± 0.05 |
| Testosterone levels (ng/dl) | 195 ± 17 | 189 ± 22 |
Animals (n = 5/group) were treated with 50 mg/kg/day of R from PND 14 to 30. At PND 90, body, testicular, and epididymal weights were assessed and blood was sampled by intracardiac puncture to determine serum parameters. Results are presented as mean ± SD.