Table 3. Unadjusted and Adjusted Risk of Any Suicide Attempt and Death by Suicide by Recency of MCI/Dementia Diagnosisa.
Model | HR (95% CI) | ||
---|---|---|---|
Unadjusted model | Model 1b | Model 2c | |
Recency of diagnosis associated with any suicide attempt (fatal or nonfatal) | |||
No MCI or dementia (n = 63 255) | 1 [Reference] | 1 [Reference] | 1 [Reference] |
Prior MCI (n = 9968) | 1.44 (1.09-1.89)d | 1.34 (1.02-1.78)d | 1.03 (0.78-1.36) |
Recent MCI (n = 11 117) | 2.00 (1.56-2.57)e | 2.10 (1.64-2.70)e | 1.73 (1.34-2.22)e |
Prior dementia (n = 40 985) | 1.52 (1.28-1.81)e | 1.50 (1.26-1.79)e | 1.14 (0.95-1.36) |
Recent dementia (n = 22 270) | 1.66 (1.35-2.04)e | 1.72 (1.40-2.12)e | 1.44 (1.17-1.77)d |
Recency of diagnosis associated with death by suicide | |||
No MCI or dementia (n = 63 255) | 1 [Reference] | 1 [Reference] | 1 [Reference] |
Prior MCI (n = 9968) | 1.11 (0.69-1.81) | 1.10 (0.68-1.79) | 0.92 (0.57-1.51) |
Recent MCI (n = 11 117) | 1.10 (0.68-1.79) | 1.12 (0.69-1.82) | 0.99 (0.61-1.61) |
Prior dementia (n = 40 985) | 0.78 (0.57-1.08) | 0.78 (0.56-1.07) | 0.64 (0.46-0.89)d |
Recent dementia (n = 22 270) | 0.93 (0.63-1.37) | 0.95 (0.64-1.39) | 0.85 (0.57-1.25) |
Abbreviations: HR, hazard ratio; MCI, mild cognitive impairment.
Includes 147 595 patients.
Adjusted for demographic characteristics (age, sex, race/ethnicity, income, and educational level) and Charlson Comorbidity Index.
Adjusted for demographic characteristics, Charlson Comorbidity Index, and any psychiatric disorder (depression, posttraumatic stress disorder, generalized anxiety disorder, alcohol abuse, drug abuse, and sleep disorder).
P < .05 compared with reference group.
P < .001 compared with reference group.