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. 2021 Mar 24;78(6):659–666. doi: 10.1001/jamapsychiatry.2021.0150

Table 3. Unadjusted and Adjusted Risk of Any Suicide Attempt and Death by Suicide by Recency of MCI/Dementia Diagnosisa.

Model HR (95% CI)
Unadjusted model Model 1b Model 2c
Recency of diagnosis associated with any suicide attempt (fatal or nonfatal)
No MCI or dementia (n = 63 255) 1 [Reference] 1 [Reference] 1 [Reference]
Prior MCI (n = 9968) 1.44 (1.09-1.89)d 1.34 (1.02-1.78)d 1.03 (0.78-1.36)
Recent MCI (n = 11 117) 2.00 (1.56-2.57)e 2.10 (1.64-2.70)e 1.73 (1.34-2.22)e
Prior dementia (n = 40 985) 1.52 (1.28-1.81)e 1.50 (1.26-1.79)e 1.14 (0.95-1.36)
Recent dementia (n = 22 270) 1.66 (1.35-2.04)e 1.72 (1.40-2.12)e 1.44 (1.17-1.77)d
Recency of diagnosis associated with death by suicide
No MCI or dementia (n = 63 255) 1 [Reference] 1 [Reference] 1 [Reference]
Prior MCI (n = 9968) 1.11 (0.69-1.81) 1.10 (0.68-1.79) 0.92 (0.57-1.51)
Recent MCI (n = 11 117) 1.10 (0.68-1.79) 1.12 (0.69-1.82) 0.99 (0.61-1.61)
Prior dementia (n = 40 985) 0.78 (0.57-1.08) 0.78 (0.56-1.07) 0.64 (0.46-0.89)d
Recent dementia (n = 22 270) 0.93 (0.63-1.37) 0.95 (0.64-1.39) 0.85 (0.57-1.25)

Abbreviations: HR, hazard ratio; MCI, mild cognitive impairment.

a

Includes 147 595 patients.

b

Adjusted for demographic characteristics (age, sex, race/ethnicity, income, and educational level) and Charlson Comorbidity Index.

c

Adjusted for demographic characteristics, Charlson Comorbidity Index, and any psychiatric disorder (depression, posttraumatic stress disorder, generalized anxiety disorder, alcohol abuse, drug abuse, and sleep disorder).

d

P < .05 compared with reference group.

e

P < .001 compared with reference group.