Table 2. Change in Scores From Baseline to 12 Months by Change in NYHA Class.
| Change | Worsening of ≥2 classes (n = 34) | Worsening of 1 class (n = 369) | No change (n = 1870) | Improvement of 1 class (n = 520) | Improvement of ≥2 classes (n = 79) |
|---|---|---|---|---|---|
| KCCQ, median (IQR) | |||||
| OS | 2 (−24 to 9) | 1 (−11 to 11) | 3 (−6 to 16) | 8 (−1 to 19) | 11 (0 to 31) |
| CSS | −5 (−22 to 9) | 0 (−13 to 11) | 3 (−7 to 16) | 6 (−2 to 21) | 8 (−1 to 27) |
| PLS | −8 (−17 to 8) | 0 (−17 to 17) | 0 (−8 to 17) | 8 (0 to 25) | 17 (0 to 42) |
| SFS | −8 (−25 to 10) | 0 (−17 to 12) | 0 (−8 to 15) | 6 (−4 to 21) | 8 (−4 to 25) |
| EQ-5D, median (IQR) | |||||
| VAS | −4 (−11 to 8) | 0 (−11 to 10) | 0 (−10 to 10) | 3 (−6 to 14) | 0 (−9 to 11) |
| Index | −0.05 (−0.13 to 0.04) | −0.01 (−0.12 to 0.04) | 0.00 (−0.06 to 0.09) | 0.01 (−0.03 to 0.13) | 0.03 (−0.01 to 0.14) |
Abbreviations: EQ-5D, EuroQoL 5-dimension; IQR, interquartile range; KCCQ-CSS, Kansas City Cardiomyopathy Questionnaire Clinical Summary Score; KCCQ-OS, Kansas City Cardiomyopathy Questionnaire Overall Summary Score; KCCQ-PLS, Kansas City Cardiomyopathy Questionnaire Physical Limitation Score; KCCQ-SFS, Kansas City Cardiomyopathy Questionnaire Symptom Frequency Score; NYHA, New York Heart Association; VAS, visual analog scale.