Table 3. Change in Scores From Baseline to 12 Months by Change in KCCQ-OS.
| Change | Worsening of ≥10 points (n = 536) | Worsening of 5-9 points (n = 234) | No change (n = 714) | Improvement of 5-9 points (n = 341) | Improvement of ≥10 points (n = 1047) |
|---|---|---|---|---|---|
| NYHA class, median (IQR) | 0 (0 to 0) | 0 (0 to 0) | 0 (0 to 0) | 0 (0 to 0) | 0 (0 to 1) |
| KCCQ, median (IQR) | |||||
| CSS | −19 (−29 to −10) | −7 (−13 to −2) | 0 (−4 to 4) | 6 (0 to 13) | 21 (13 to 33) |
| PLS | −21 (−33 to −8) | −8 (−17 to 0) | 0 (−8 to 8) | 8 (0 to 17) | 25 (8 to 40) |
| SFS | −17 (−33 to −6) | −6 (−15 to 0) | 0 (−8 to 6) | 4 (−4 to 13) | 19 (8 to 33) |
| EQ-5D, median (IQR) | |||||
| VAS | −9 (−20 to 2) | −3 (−15 to 5) | 0 (−8 to 9) | 1 (−8 to 11) | 6 (−3 to 20) |
| Index | −0.06 (−0.17 to 0.00) | −0.02 (−0.13 to 0.01) | 0.00 (−0.06 to 0.05) | 0.00 (−0.02 to 0.11) | 0.05 (−0.01 to 0.15) |
Abbreviations: EQ-5D, EuroQoL 5-dimension; IQR, interquartile range; KCCQ-CSS, Kansas City Cardiomyopathy Questionnaire Clinical Summary Score; KCCQ-OS, Kansas City Cardiomyopathy Questionnaire Overall Summary Score; KCCQ-PLS, Kansas City Cardiomyopathy Questionnaire Physical Limitation Score; KCCQ-SFS, Kansas City Cardiomyopathy Questionnaire Symptom Frequency Score; NYHA, New York Heart Association; VAS, visual analog scale.