Table 2. Clinical Results by Genotypea,b.
|
IEF/HPLC |
||||||||
---|---|---|---|---|---|---|---|---|---|
A | AA | AS | SS | total | B | sensitivity | specificity | accuracy | |
assay predictions | AA | 33 | 0 | 0 | 33 | AA | 97.1% (33/34) | 100.0% (57/57) | 95.6% (87/91) |
AS | 1 | 0 | 3 | 4 | |||||
SS | 0 | 0 | 54 | 54 | SS | 94.7% (54/57) | 100.0% (34/34) | ||
total | 34 | 0 | 57 | 91 |
(A) Confusion matrix of genotypes identified by this assay compared to those obtained by IEF/HPLC gold standard for the 91 AA and SS samples.
(B) Sensitivity, specificity, and overall accuracy by genotype.