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. 2021 Mar 15;6(11):7711–7718. doi: 10.1021/acsomega.1c00035

Table 2. Clinical and Hematological Parameters of the CML Patients Examined at the Baseline and Later during the Follow Up after the Initiation of Imatinib Treatment, at 1.5 Months, 3 Months, 6 Months, and 12 Months.

parameters ⇒ (N = 36) (*in peripheral blood sample) Hb gm % TLC (103/μL)* platelet count (103/μL)* eosinophils (%)* basophils (%)* blasts (%)* spleen size (cms below costal margin)
at baseline before therapy mean ± SD 9.8 ± 1.88 210 ± 117 301 ± 91 3.4 ± 2 4.8 ± 3.9 2.9 ± 2.2 6.6 ± 3.1
  median (interquartile range) 9.35 (8.6–11.2) 207 (103–261) 290 (239–403) 3 (2–4) 4 (2–6) 2 (2–3) 6 (5–7)
after 1.5 months of imatinib therapy mean ± SD 10.5 ± 1.74 30 ± 74 280 ± 90 3.7 ± 2.4 4 ± 3.6 2.5 ± 5 splenomegaly not found in 14 patients
  median (interquartile range) 10.7 (9.17–11.5) 16 (9–27) 272 (228–350) 3 (2–5) 3 (2–6) 2 (0–3)  
after 3 months of imatinib therapy mean ± SD 12.5 ± 1.69 21 ± 61 238 ± 114 2.6 ± 1.6 1.9 ± 3.3 0.9 ± 4.3 splenomegaly not found in 29 patients
  median (interquartile range) 12.7 (11.38–13.4) 11 (8–12) 205 (148–310) 2 (2–3) 1.5 (0–2) 0 (0–0)  
after 6 months of imatinib therapy mean ± SD 12.7 ± 1.61 15 ± 39 214 ± 80 2.8 ± 1.5 0.8 ± 1.3 0.7 ± 3 splenomegaly not found in 32 patients
  median (interquartile range) 12.85 (11.6–13.6) 8 (6–10) 202 (153–267) 2.5 (2–3) 0.5 (0–1) 0 (0–0)  
after 12 months of imatinib therapy mean ± SD 12.77 ± 1.55 13 ± 37 220 ± 117 2.3 ± 2 1 ± 2.8 0.7 ± 4 splenomegaly not found in 35 patients
  median (interquartile range) 13 (11.81–13.78) 6 (5–8) 201 (139–250) 2 (1–3) 0 (0–1) 0 (0–0)