Table 4.
Association of chest CT imaging interpretations with MDD consensus clinical diagnoses in 150 of 179 patients
| Chest CT Imaging Interpretation | MDD Consensus Clinical Diagnosis | n |
|---|---|---|
| Usual interstitial pneumonia (UIP) (n = 31) |
Idiopathic pulmonary fibrosis (IPF) | 17 |
| Autoimmune-related ILD | 8 | |
| Chronic hypersensitivity pneumonitis (HP) | 2 | |
| Medication-induced ILD | 2 | |
| Occupation-related ILD | 1 | |
| Unclassifiable ILD * | 1 | |
| Nonspecific interstitial pneumonia (NSIP) (n = 21) |
Autoimmune-related ILD | 11 |
| Chronic hypersensitivity pneumonitis (HP) | 4 | |
| Medication-induced ILD | 1 | |
| Acute interstitial pneumonia (AIP) | 1 | |
| Idiopathic NSIP | 1 | |
| Unclassifiable ILD * | 3 | |
| Organizing pneumonia (OP) (n = 16) |
Autoimmune-related ILD | 10 |
| Chronic hypersensitivity pneumonitis (HP) | 2 | |
| Medication-induced ILD | 1 | |
| Acute interstitial pneumonia (AIP) | 1 | |
| Unclassifiable ILD * | 2 | |
| Multifocal ground glass opacities (GGO) (n = 16) |
Medication-induced ILD | 4 |
| Autoimmune-related ILD | 2 | |
| Smoking-related ILD | 2 | |
| Chronic hypersensitivity pneumonitis (HP) | 1 | |
| Other ‡ | 4 | |
| Unclassifiable ILD * | 3 | |
| Widespread mosaicism (n = 13) |
Chronic hypersensitivity pneumonitis (HP) | 4 |
| Autoimmune-related ILD | 2 | |
| Medication-induced ILD | 1 | |
| Occupation-related ILD | 1 | |
| Other ¶ | 3 | |
| Unclassifiable ILD * | 2 | |
| Unclassifiable fibrosis † (n = 25) |
Chronic hypersensitivity pneumonitis (HP) | 8 |
| Occupation-related ILD | 3 | |
| Medication-induced ILD | 2 | |
| Smoking-related ILD | 1 | |
| Unclassifiable ILD * | 11 | |
| Smoking-related ILD (n = 17) |
Smoking-related ILD | 14 |
| Chronic hypersensitivity pneumonitis (HP) | 2 | |
| Autoimmune-related ILD | 1 | |
| Chronic hypersensitivity pneumonitis (HP) (n = 11) |
Chronic hypersensitivity pneumonitis (HP) | 8 |
| Occupation-related ILD | 1 | |
| Unclassifiable ILD * | 2 | |
*
unclassifiable ILD indicates two or more ILD diagnoses remained under consideration or ILD remained unclassifiable.
†
unclassifiable fibrosis indicates radiologic findings of pulmonary fibrosis were present, but more specific radiologic patterns of fibrosis were absent.
‡
chronic aspiration (n = 1), constrictive bronchiolitis (n = 1), post-infectious ILD (n = 1), chronic eosinophilic pneumonia (n = 1).
¶
idiopathic pulmonary hemosiderosis (n = 1), constrictive bronchiolitis (n = 1), congenital bronchopulmonary dysplasia (n = 1).