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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Respir Med. 2021 Feb 11;179:106333. doi: 10.1016/j.rmed.2021.106333

Table 5.

Association of surgical lung biopsy (SLB) interpretations with MDD consensus clinical diagnoses in 41 of 56 patients

SLB Histopathologic Interpretation MDD Consensus Clinical Diagnosis n
Usual interstitial pneumonia (UIP)
(n = 12)
Idiopathic pulmonary fibrosis (IPF) 4
Medication-induced ILD 2
Autoimmune-related ILD 1
Chronic hypersensitivity pneumonitis (HP) 1
Occupation-related ILD 1
Unclassifiable ILD * 3

Nonspecific interstitial pneumonia (NSIP)
(n = 12)
Chronic hypersensitivity pneumonitis (HP) 5
Autoimmune-related ILD 3
Idiopathic pulmonary fibrosis (IPF) 1
Acute interstitial pneumonia (AIP) 1
Idiopathic NSIP 1
Unclassifiable ILD * 1

Unclassifiable fibrosis
(n = 9)
Smoking-related ILD 5
Chronic hypersensitivity pneumonitis (HP) 1
Unclassifiable ILD * 3

Organizing pneumonia (OP)
(n = 4)
Autoimmune-related ILD 4

Hypersensitivity pneumonitis
(n = 4)
Chronic hypersensitivity pneumonitis (HP) 4
*

unclassifiable ILD indicates two or more ILD diagnoses remained under consideration or ILD remained unclassifiable.

unclassifiable fibrosis indicates histologic findings of pulmonary fibrosis were present, but more specific histopathologic patterns of fibrosis were absent.