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. 2021 Mar 23;218(5):e20201974. doi: 10.1084/jem.20201974

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© 2021 Chen et al.

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Figure S1. — DEK deletion impairs hematopoiesis in mice. (A) PB complete blood cell counts of Dek^fl/fl and Dek-cKO mice at 1.5 and 3 mo of age (n = 5–7). WBC, white blood cells; NE, neutrophils; LY, lymphocytes; MO, monocytes; EO, eosinophils; BA, basophils; PLT, platelets; Hb, hemoglobin. (B and C) Weight analysis and BM cells count in Dek^fl/fl and Dek-cKO mice at 3 mo of age (n = 6). (D) FACS analysis of myeloid cells (Mac⁺Gr1⁺), red cells (R1: Ter119^medCD71^high; R2: Ter119^highCD71^high; R3: Ter119^highCD71^med; R4: Ter119^highCD71^low), B cells (immature B: IgM⁻B220⁺; mature B: IgM⁺B220⁺), and T cells (immature T: CD8a⁺CD4⁺; CD4⁺ T; CD8⁺ T) in BM, spleen, and thymus of Dek^fl/fl and Dek-cKO mice at 3 mo of age. (E and F) Percent analysis of myeloid cells in BM and spleen cells (n = 5). (G and H) Percent analysis of red cells in BM and spleen cells (n = 5). (I and J) Percent analysis of B cells in BM and spleen cells (n = 5). (K and L) Percent analysis of T cells in spleen and thymus cells (n = 5). Error bars represent means ± SD. **, P < 0.01; ***, P < 0.001; Student’s t test. Data are representative of three independent experiments.