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. 2021 Mar 11;11:628807. doi: 10.3389/fonc.2021.628807

Figure 3.

Figure 3

Mutational profiles of post-treatment tumor samples of relapsed/refractory diffuse large B-cell lymphoma (rrDLBCL) and pretreatment tumor samples of cured DLBCL. rrDLBCL patients include 28 refractory, 14 early recurred, and 5 late recurred patients. Genes mutated in > 3 samples and pathways having > 1 mutated genes are shown. The pathways and genes are ordered by the frequency of mutation. Copy numbers > 6 are marked as amplifications and copy numbers < 0.8 are marked as deletions. COO, cell of origin; ABC, activated B-cell-like subtype; GCB, germinal center B-cell-like subtype.