Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 23;218(4):e20201605. doi: 10.1084/jem.20201605

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Okła et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 2. — T_RM in cancer immunotherapy. Several strategies have been proposed to enhance T_RM activity. Checkpoint blockade may enhance intratumoral proliferation of T_RM. DCs may be used as a vaccine to induce functional T_RM. Targeting specific transcription factors and cytokines may drive T_RM formation and may boost induction of active T_RM. Targeting particular metabolites (e.g., FFA and FABP) may promote T_RM pool and antitumor activity. Adoptive transfer of preprogramed T_RM or T_SCM may improve T_RM seeding or differentiation, thereby enhancing antitumor immunity. PPAR, peroxisome proliferator–activated receptor.