Myocardial contrast echocardiography (top) and 99mTc-sestamibi SPECT images (bottom) at rest (right panel) and stress (left panel). White arrows depict reversible perfusion defects that are caused by capillary de-recruitment in a patient with left circumflex artery stenosis. At rest, perfusion (capillary density) was normal and equal to the contralateral left anterior descending artery bed while during hyperemia the capillary density decreased in the left circumflex compared to the left anterior descending artery bed. Reprinted with permission from Kaul et al. [9]§.
§Reprinted from Kaul S., Senior, R., Dittrich, H., Raval, U., Khattar, R. and Lahiri, A. Detection of coronary artery disease with myocardial contrast echocardiography: comparison with 99mTc-sestamibi single-photon emission computed tomography. Circulation, 1997. 96(3): p. 785–92. DOI: 10.1161/01.CIR.96.3.785. Copyright (1997), with permission from Wolters Kluwer Health, Inc.; License # 4850970686370 (June, 2020).