Table 1. Demographic data and clinical characteristics of patients at baseline visit.
| Characteristic | Normal weight group (n=20) | p-value* | Weight maintenance group (n=12) | Weight reduction group (n=8) | p-value† |
|---|---|---|---|---|---|
| Age (yr) | 28.05±5.70 | 0.044 | 42.42±15.70 | 26.25±11.11 | 0.022 |
| Sex | 0.744 | 0.085 | |||
| Male | 8 (40.0) | 6 (50.0) | 1 (12.5) | ||
| Female | 12 (60.0) | 6 (50.0) | 7 (87.5) | ||
| BMI at baseline (kg/m2) | 22.04±2.18 | <0.001 | 27.23±2.03 | 30.73±5.40 | 0.054 |
| EASI | 8.9±5.72 | 0.003 | 16.64±9.25 | 15.59±7.71 | 0.793 |
| VAS for pruritus | 5.05±2.33 | 0.076 | 6.83±1.40 | 5.38±2.07 | 0.075 |
| Eosinophil count (103/µl) | 0.61±0.70 | 0.414 | 0.34±0.31 | 0.59±0.57‡ | 0.262 |
| Total IgE (IU/ml) | 932.11±1,147.72§ | 0.374 | 1,580.23±960.58∥ | 1,185.4±1,180.68¶ | 0.585 |
| TARC | 303.19±83.52 | 0.007 | 259.36±65.14 | 193.66±68.75 | 0.044 |
Values are presented as mean±standard deviation or number (%). BMI: body mass index, EASI: Eczema Area and Severity Index, VAS: visual analogue scale, IgE: immunoglobulin E, TARC: thymus and activaton-regulated chemokine. *p-value between normal weight group and obese group, †p-value between weight maintenance group and weight loss group, ‡n=10, §n=16, ∥n=4, ¶n=7.