Table 1. Comparison of study variables with positive and negative autologous serum and positive test groups.
| Study variable | ASST−/APST− | ASST−/APST+ | ASST+/APST− | ASST+/ASST+ | p-value |
|---|---|---|---|---|---|
| Patients counts (n=300) | 175 | 12 | 57 | 56 | |
| Age | 35.97±12.12 | 38.08±12.18 | 34.11±12.87 | 35.29±14.28 | 0.697 |
| Sex | 0.230 | ||||
| Male | 81 (46.3) | 2 (16.7) | 26 (45.6) | 28 (50.0) | |
| Female | 94 (53.7) | 10 (83.3) | 31 (54.4) | 28 (50.0) | |
| Duration (wk) | 95.95±175.74 | 70.08±147.37 | 56.30±101.89 | 45.86±117.01 | 0.004* |
| Episode(s) of angioedema | 11 (6.3) | 2 (16.7) | 11 (19.3) | 11 (19.6) | 0.005* |
| History of atopy | 20 (11.4) | 3 (25.0) | 9 (15.8) | 5 (8.9) | 0.336 |
| Treatment level | 0.432 | ||||
| 1 | 142 (84.0) | 11 (91.7) | 50 (89.3) | 51 (92.7) | |
| 2 | 21 (12.4) | 1 (8.3) | 4 (7.1) | 2 (3.6) | |
| 3 | 3 (1.8) | 0 (0.0) | 2 (3.6) | 0 (0.0) | |
| 4 | 3 (1.8) | 0 (0.0) | 0 (0.0) | 2 (3.6) | |
| C3 (mg/dl) | 111.37±18.88 | 103.37±13.58 | 104.64±20.42 | 108.41±22.22 | 0.497 |
| C4 (mg/dl) | 26.99±7.38 | 29.66±9.60 | 26.13±5.89 | 24.93±9.18 | 0.439 |
| Total IgE (IU/ml) | 262.60±368.57 | 163.50±140.86 | 225.72±201.72 | 173.23±116.62 | 0.598 |
| Eosinophil count (%) | 2.73±1.83 | 2.85±1.51 | 2.67±1.75 | 2.29±1.46 | 0.375 |
| Platelet count (109/L) | 253.96±54.03 | 234.00±50.58 | 259.43±51.44 | 257.63±65.84 | 0.313 |
| Thyroid function test | |||||
| TSH (mU/L) | 2.04±1.74 | 1.63±1.14 | 2.24±1.94 | 4.91±16.36 | 0.460 |
| T3 (ng/dl) | 111.65±29.99 | 107.00±14.70 | 113.28±19.46 | 108.60±21.71 | 0.445 |
| Free T4 (ng/dl) | 1.28±0.35 | 1.28±0.19 | 1.27±0.18 | 1.27±0.27 | 0.812 |
| Thyroid antibodies | |||||
| Anti-TSH-R (U/L) | 0.62±1.17 | 0.70±0.38 | 0.43±0.25 | 0.48±0.27 | 0.079 |
| Anti-TPO (IU/ml) | 120.98±509.32 | 71.69±173.70 | 145.30±371.63 | 157.60±498.87 | 0.059 |
| Anti-TG (IU/ml) | 71.07±279.95 | 29.68±39.15 | 32.88±45.84 | 71.67±186.24 | 0.593 |
Values are presented as number only, number (%), or mean±standard deviation. APST: autologous plasma skin test, ASST: autologous serum skin test, −: negative, +: positive, TG: thyroglobulin, TPO: thyroid peroxidase, TSH: thyroid stimulating hormone, TSH-R: thyroid stimulating hormone receptor, IgE: immunoglobuline E. *p-value of <0.05.