Table 2. Univariable analysis for the association between autologous serum and plasma skin test results and clinical and laboratory characteristics in chronic spontaneous urticaria.
| Variable | Category | ASST | APST | ||
|---|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | ||
| Age | 0.99 (0.97~1.01) | 0.349 | 1.00 (0.98~1.02) | 0.877 | |
| Sex | 0.567 | 0.771 | |||
| Male | Reference | Reference | |||
| Female | 0.87 (0.55~1.39) | 0.567 | 1.08 (0.63~1.88) | 0.771 | |
| Eosinophil count | 0.91 (0.79~1.05) | 0.225 | 0.88 (0.73~1.05) | 0.178 | |
| TSH level | 1.07 (0.99~1.26) | 0.383 | 1.05 (0.99~1.22) | 0.313 | |
| T3 level | 1.00 (0.99~1.01) | 0.899 | 0.99 (0.98~1.01) | 0.442 | |
| fT4 level | 0.93 (0.31~2.37) | 0.875 | 0.93 (0.24~2.64) | 0.907 | |
| ANA positivity | 0.142 | 0.848 | |||
| 0 | Reference | Reference | |||
| 1 | 0.37 (0.14~0.87) | 0.022 | 0.65 (0.22~1.62) | 0.376 | |
| 2 | 0.78 (0.13~3.60) | 0.754 | 0.83 (0.08~4.27) | 0.837 | |
| 3 | 0.47 (0.00~8.88) | 0.625 | 1.01 (0.01~19.26) | 0.994 | |
| C3 level | 0.99 (0.97~1.01) | 0.273 | 0.99 (0.97~1.01) | 0.471 | |
| C4 level | 0.97 (0.92~1.01) | 0.173 | 0.99 (0.94~1.04) | 0.639 | |
| Treatment level | 0.330 | 0.213 | |||
| 1 | Reference | Reference | |||
| 2 | 0.41 (0.15~1.00) | 0.064 | 0.42 (0.11~1.19) | 0.109 | |
| 3 | 1.01 (0.13~6.20) | 0.991 | 0.28 (0.00~2.53) | 0.308 | |
| 4 | 1.01 (0.13~6.20) | 0.991 | 2.20 (0.36~11.57) | 0.363 | |
| Angioedema | 0.002 | 0.033 | |||
| Absent | Reference | Reference | |||
| Present | 3.24 (1.58~6.89) | 0.002 | 2.26 (1.05~4.71) | 0.033 | |
| History of atopy | 0.911 | 0.799 | |||
| Absent | Reference | Reference | |||
| Present | 0.96 (0.46~1.92) | 0.911 | 0.90 (0.37~1.98) | 0.799 | |
| High TPO | 0.470 | 0.754 | |||
| Absent | Reference | Reference | |||
| Present | 1.36 (0.58~3.08) | 0.470 | 1.17 (0.41~2.92) | 0.754 | |
| High TG | 0.269 | 0.212 | |||
| Absent | Reference | Reference | |||
| Present | 0.63 (0.27~1.38) | 0.269 | 0.50 (0.14~1.34) | 0.212 | |
| High TSH-R | 0.129 | 0.413 | |||
| Absent | Reference | Reference | |||
| Present | 0.17 (0.00~1.51) | 0.129 | 0.35 (0.00~3.15) | 0.413 | |
| Platelet count | 1.21 (0.79~1.85) | 0.389 | 0.95 (0.57~1.55) | 0.829 | |
| Total IgE level | 0.93 (0.82~1.02) | 0.147 | 0.84 (0.70~0.98) | 0.057 | |
| Disease duration | 0.79 (0.63~0.95) | 0.025 | 0.81 (0.61~1.01) | 0.099 | |
APST: autologous plasma skin test, ASST: autologous serum skin test, ANA: antinuclear antibody, OR: odd ratio, CI: confidence interval, TG: thyroglobulin, TPO: thyroid peroxidase, TSH: thyroid stimulating hormone, TSH-R: thyroid stimulating hormone receptor, IgE: immunoglobuline E.