Table 1. The gut microbiome in inflammatory skin diseases.
Inflammatory skin diseases | Reference |
---|---|
Atopic dermatitis (AD) | |
• Escherichia coli in the gut increases the risk of developing eczema. | Penders et al.43 |
• Clostridioides difficile in the gut increases the risk of all atopic outcomes. | Penders et al.43 |
• Bifidobacterium in the gut is decreased in AD and the decrease is correlated with severity of AD symptoms. | Watanabe et al.45 |
• Certain gut microbiota are enriched in AD children with food allergy. | Fieten et al.46 |
Psoriasis | |
• Clostridiales and Erysipelotrichales in the gut are necessary for induction of imiquimod-induced psoriasis-like dermatitis. | Zákostelská et al.57 |
• Akkermansia muciniphila is decreased in the gut of psoriasis patients. | Tan et al.59 |
• Bacteroides and Proteobacteria are decreased and Actinobacteria and Firmicutes are increased in the gut of psoriasis patients. | Hidalgo-Cantabrana et al.60 |
• Actinobacteria and Firmicutes are increased in the gut of psoriasis patients. | Shapiro et al.61 |
• “Psoriatic core intestinal microbiome” is associated with increased lipopolysaccharides function and bacterial translocation into peripheral blood. | Shapiro et al.61 |
Rosacea | |
• SIBO treatment with rifaximin in rosacea patients demonstrated resolution of skin symptoms. | Parodi et al.67 |
• Gut dysbiosis was demonstrated in a group of Korean female rosacea patients. | Nam et al.69 |
SIBO: small intestinal bacterial overgrowth.