Fig. 6. The changes in skin barrier function, skin hydration, 1-deoxysphingosine levels, and the effect of physiological lipid mixture (PL) treatment on 1-deoxysphingosine production in the skin of an X-ray irradiated hairless mouse: (A) transepidermal water loss (TEWL) in the hairless mouse increased after X-ray irradiation (normal control vs. X-ray, p<0.001), but not in the group treated with physiological lipid mixture (X-ray vs. X-ray+PL, p<0.001). Each determination was made in triplicate, and data represent the mean±standard deviation (SD). (B) Skin hydration (arbitrary units, AU) of the hairless mouse improved in the physiological lipid mixture treatment group (normal control vs. X-ray+PL, p<0.001, X-ray vs. X-ray+PL, p<0.001). Each determination was made in triplicate, and data represent the mean±SD. ***p<0.001.
