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. 2020 Jun 30;32(4):306–318. doi: 10.5021/ad.2020.32.4.306

Table 2. The production of 1-deoxyceramide after X-ray irradiation.

X-ray dose (Gy) Irradiation time (h) N-acyl chain length
C16 C18 C20 C22 C24 C24:1
3 0 12.80±1.03 3.95±0.24 3.62±0.34 2.80±0.22 13.76±1.05 12.28±1.13
12 14.41±1.41 4.85±0.75 3.71±0.25 5.46±0.58 13.33±0.94 12.69±1.56
18 15.50±1.21** 4.96±0.34 3.71±0.34 6.49±0.45 16.30±1.21 15.68±1.09***
24 17.11±1.07*** 6.05±0.75** 6.57±0.69*** 6.28±0.69*** 27.98±1.53*** 17.07±0.46***
6 0 13.26±1.24 3.08±0.33 2.65±0.53 2.86±0.25 11.58±1.03 11.75±1.04
12 15.80±1.08 5.34±0.42 3.57±0.43 5.20±0.13 16.12±1.29** 13.20±0.25
18 20.80±1.98*** 6.63±0.78*** 5.06±0.65 6.41±0.87*** 22.42±1.22*** 16.34±1.98*
24 22.52±3.87*** 7.51±0.54*** 8.17±1.09*** 8.58±0.48*** 32.14±2.52*** 23.9±3.25***

Values are presented as mean±standard deviation (pmol/mg). *p<0.05, **p<0.01, and ***p<0.001 compared to untreated normal human epidermal keratinocytes.