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. 2020 Jun 30;32(4):306–318. doi: 10.5021/ad.2020.32.4.306

Table 3. The production of 1-deoxydihydroceramide after X-ray irradiation.

X-ray dose (Gy) Irradiation time (h) N-acyl chain length
C16 C18 C20 C22 C24 C24:1
3 0 24.66±2.04 6.43±0.25 3.06±0.29 4.29±0.49 2.05±0.31 1.78±0.18
12 23.15±1.09 6.75±0.84 3.63±0.48 3.52±0.26 2.15±0.25 1.93±0.18
18 24.01±1.87 7.54±0.36 3.72±0.36 3.69±0.36 2.24±0.21 1.69±0.24
24 27.99±1.94 10.35±0.75*** 3.04±0.33 4.59±0.47 3.63±0.37*** 1.72±0.33
6 0 23.58±1.83 6.88±0.42 3.15±0.34 3.00±0.16 3.09±0.24 1.59±0.36
12 26.35±2.52 7.42±0.45 2.86±0.21 3.20±0.21 3.96±0.45 1.69±0.25
18 28.50±2.84 9.42±1.21 3.49±0.51 3.61±0.33 4.08±0.41 1.27±0.11
24 30.93±3.21** 11.61±1.25*** 3.44±0.41 5.47±0.46*** 5.20±0.58** 2.80±0.14

Values are presented as mean±standard deviation (pmol/mg). **p<0.01, and ***p<0.001 compared to untreated normal human epidermal keratinocytes.