Table 2. Univariable and multivariable analyses of the effects of various factors on treatment response.
| Factors | Tx response (n=84) | Univariableanalysis | Multivariableanalysis | |||
|---|---|---|---|---|---|---|
| Good (n=26) | Moderate (n=31) | Poor (n=20) | Resistant (n=7) | p-value | p-value | |
| Sex | ||||||
| Female | 13 (26.5) | 20 (40.8) | 12 (24.5) | 4 (8.2) | Ref. | - |
| Male | 13 (37.1) | 11 (31.4) | 8 (22.9) | 3 (8.6) | 0.4192 | |
| Age (y) | ||||||
| y<10 | 7 (58.3) | 5 (41.7) | 0 (0.0) | 0 (0.0) | Ref. | Ref. |
| 10≤y<20 | 3 (20.0) | 2 (13.3) | 8 (53.3) | 2 (13.3) | 0.0555 | 0.5306 |
| 20≤y<30 | 9 (37.5) | 8 (33.3) | 7 (29.2) | 0 0.0 | 0.4719 | 0.7868 |
| 30≤y<40 | 2 (16.7) | 8 (66.7) | 0 (0.0) | 2 (16.7) | 0.0135‡ | 0.2289 |
| 40≤y<50 | 1 (11.1) | 4 (44.4) | 2 (22.2) | 2 (22.2) | 0.1647 | 0.0908 |
| 50≤y | 4 (33.3) | 4 (33.3) | 3 (25.0) | 1 (8.3) | 0.6548 | 0.2560 |
| Location | ||||||
| Forehead | 5 (26.3) | 9 (47.4) | 5 (26.3) | 0 0.0 | 1 | 0.9783 |
| Nose | 4 (36.4) | 4 (36.4) | 2 (18.2) | 1 (9.1) | 0.0960 | 0.7947 |
| Perioral area | 2 (15.4) | 2 (15.4) | 6 (46.2) | 3 (23.1) | Ref. | Ref. |
| Cheek | 8 (26.7) | 13 (43.3) | 7 (23.3) | 2 (6.7) | 0.9076 | 0.3087 |
| Periocular area | 7 (63.6) | 3 (27.3) | 0 (0.0) | 1 (9.1) | 0.1707 | 0.0324‡ |
| Cause | ||||||
| Trauma | 12 (41.4) | 8 (27.6) | 8 (27.6) | 1 (3.4) | 0.9636 | - |
| Operation | 14 (31.8) | 18 (40.9) | 7 (15.9) | 5 (11.4) | Ref. | |
| Burn | 0 (0.0) | 1 (25.0) | 3 (75.0) | 0 (0.0) | 0.2085 | |
| Others | 0 (0.0) | 4 (57.1) | 2 (28.6) | 1 (14.3) | 0.3210 | |
| Type | ||||||
| Flat | 9 (47.4) | 8 (42.1) | 0 (0.0) | 2 (10.5) | 0.1281 | 0.8692 |
| Atrophic | 3 (23.1) | 5 (38.5) | 5 (38.5) | 0 0.0 | 1 | 0.9336 |
| Hypertrophic | 6 (18.8) | 9 (28.1) | 13 (40.6) | 4 (12.5) | Ref. | Ref. |
| Adhesive | 8 (40.0) | 9 (45.0) | 2 (10.0) | 1 (5.0) | 1 | 0.4550 |
| Onset of Tx (m)* | ||||||
| m<1 | 11 (50.0) | 8 (36.4) | 3 (13.6) | 0 0.0 | Ref. | Ref. |
| 1≤m<6 | 6 (37.5) | 5 (31.3) | 2 (12.5) | 3 (18.8) | 0.6243 | 0.3576 |
| 6≤m | 9 (19.6) | 18 (39.1) | 15 (32.6) | 4 (8.7) | 0.0028‡ | 0.0035‡ |
| Initial VSS | ||||||
| <5 | 17 (42.5) | 11 (27.5) | 9 (22.5) | 3 (7.5) | Ref. | - |
| ≥5 | 9 (20.5) | 20 (45.5) | 11 (25.0) | 4 (9.1) | 0.1479 | |
| Laser modality† | ||||||
| PDL only | 3 (60.0) | 2 (40.0) | 0 (0.0) | 0 (0.0) | Ref. | Ref. |
| NAFL only | 22 (44.0) | 18 (36.0) | 9 (18.0) | 1 (2.0) | 0.5576 | 0.1439 |
| PDL, NAFL both | 1 (3.4) | 11 (37.9) | 11 (37.9) | 6 (20.7) | 0.0176‡ | 0.0011‡ |
| Corticosteroidinjection | ||||||
| No | 22 (100.0) | 0 (0.0) | 0 (0.0) | Ref. | - | |
| Yes | 4 (6.5) | 31 (50.0) | 20 (32.3) | 7 (11.3) | 0.3618 | |
Values are presented as number (%). Percentages may not add up to 100 due to rounding. Tx: treatment, y: years, m: months, VSS: Vancouver scar scale, PDL: 595-nm pulsed-dye laser, NAFL: non-ablative fractional laser, Ref.: reference. *The period between the injury and initiation of laser treatment. †Used laser modalities were selected via an algorithm according to the state of individual scars. ‡p<0.05.