Fig. 2. (A) Histopathological findings of group A, group B and group C at week 4 (H&E, ×200). (B) Changes in epidermal thickness. The epidermal thickness of the inflammatory nodules decreased with time, especially in group C, followed by group B and group A. However, there were no statistically significant differences. (C) Changes in the number of microcomedone-like cysts. The number of microcomedone-like cysts decreased with time, especially in group C, followed by group B and group A. However, there were no statistically significant differences. (D) Changes in the size of microcomedone-like cysts. The size of the microcomedone-like cysts decreased with time, especially in group C, followed by group B and group A. However, there were no statistically significant differences.