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. 2019 Jul 1;31(4):454–457. doi: 10.5021/ad.2019.31.4.454

Table 1. pDCs presence and MxA expression in pemphigus versus pemphigoid group (%).

Entity (case no.) Age (yr) Gender (ratio) Frequency of pDC infiltration pDC score* MxA score
0 1 2 3 0 1 2
Pemphigus (n=46) 6~81 20 M:26 F 46 0 16 29 1 0 44 2
Pemphigoid (n=32) 47~91 14 M:18 F 23 9 17 6 0 9 23 0
p-value - - <0.05 <0.05 <0.05

pDCs: plasmacytoid dendritic cells, MxA: myxovirus resistance A, M: male, F: female. *BDCA2+ pDC content was scored as percentage of total mononuclear infiltrate: 0 (no positive cells), 1 (1%~10% positive cells), 2 (10%~50% positive cells), 3 (>50% positive cells). MxA staining was scored as: 0=negative, 1=patchy/weak, and 2=diffuse. Statistical analysis was performed by using the Mann-Whitney test to analyze statistical differences in pDC and MxA scores between the 2 groups. A two-tailed p-value of <0.05 was considered statistically significant. Normal skin tissue served as negative control and cutaneous lupus erythematosus served as positive control.