Fig. 1.

Number of macrophages and level of cytokines/chemokines in crushed sciatic nerves from WT and Cryab^−/− animals. a Representative images and quantification of the number of Iba1⁺ profiles in the sciatic nerves of naïve (N), and 1, 3, 5, 7, 14, 21, and 28 days post-crushed WT (white bars) and Cryab^−/− (black bars) animals; representative of 2 experiments, n = 3–5 animals/group, magnification = × 20, bar = 20 μm, data represent mean ± sem, *p < 0.05 independent t-test. b–e Concentration of IL-6 (a), IL-1β (b), TNF-α (c) and MCP-1 (d) in the distal sciatic nerve segments of naïve (N), and 1, 3, 5, 7, 14, 21, and 28 days post-crushed WT (white bars) and Cryab^−/− (black bars) mice. Representative of 2 experiments, n = 3–4 mice/group. Data represent mean ± sem, *p < 0.05 independent t-test