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. 2021 Mar 25;21:151. doi: 10.1186/s12886-021-01906-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Definition and calculation of BMO-MRW and BMO-MRA. For each subject, 48 BMOs were obtained by 24 angularly equidistant radial B-scans (4 of the 24 B-scans are shown in the picture). BMO-MRW was the minimum distance between BMO and the ILM (blue arrow). BMO-MRA was the minimum surface between every two adjacent BMOs and the ILM (the area surrounded by the yellow arrows). The BMO-MRA value was determined by summing the areas of those minimum surfaces in each sector or globally