Fig. 3.

Modeled intelligence endpoints at 3 years post-RT, by dose to brain substructure, age at RT, and presence of VP shunt (D50 = dose to 50% of the structure). Solid lines represent patients without VP shunt, while dotted lines represent patients with a VP shunt. Line colors represent age at RT: 3 years (red), 6 years (yellow-green), 9 years (dark green), 12 years (blue), 15 years (purple). (A) Full scale IQ. (B) Processing speed. (C) Verbal comprehension. (D) Working memory. Perceptual reasoning was not included because its relationship with dose was not statistically significant.