Table 2.
Neurocognitive function test at baseline and changes from baseline at 4 and 6 months *
HA-WBRT | C-WBRT | P-value | |
---|---|---|---|
Baseline neurocognitive function | |||
N = 33 | N = 32 | ||
HVLT-R Total Recall | 18.61 (16.98 to 20.33) | 19.00 (17.11 to 20.89) | 0.754 |
HVLT-R Delayed Recall | 5.88 (4.86 to 6.80) | 6.06 (5.06 to 7.06) | 0.794 |
HVLT-R Recognition Index | 10.30 (9.48 to 11.12) | 10.47 (9.87 to 11.07) | 0.742 |
TMT-A | 49.52 (42.55 to 56.50) | 54.28 (39.51 to 69.05) | 0.551 |
TMT-B | 79.18 (68.89 to 89.48) | 86.59 (63.55 to 109.64) | 0.547 |
COWA | 18.73 (16.49 to 20.97) | 17.10 (14.44 to 19.75) | 0.340 |
Changes from baseline to 4 months after WBRT | |||
N = 25 | N = 24 | ||
HVLT-R Total Recall | +0.84 (−1.68 to +3.36) | +1.67 (−0.73 to +4.06) | 0.626 |
HVLT-R Delayed Recall | −0.52 (−1.62 to +0.58) | +0.25 (−0.86 to +1.36) | 0.313 |
HVLT-R Recognition Index | −1.72 (−3.32 to −0.12) | −0.96 (−1.83 to −0.09) | 0.392 |
TMT-A | +15.67 (−4.77 to +36.11) | +1.56 (−3.30 to +6.41) | 0.177 |
TMT-B | +24.36 (−2.89 to +51.61) | +9.71 (−8.40 to 27.83) | 0.361 |
COWA | −0.48 (−2.87 to +1.91) | +1.65 (−0.81 to +4.12) | 0.205 |
Changes from baseline to 6 months after WBRT | |||
N = 17 | N = 20 | ||
HVLT-R Total Recall | +1.65 (−1.68 to +3.36) | −0.95 (−2.75 to +0.85) | 0.079 |
HVLT-R Delayed Recall | +0.35 (−0.74 to +1.44) | −0.65 (−1.64 to +0.34) | 0.160 |
HVLT-R Recognition Index | +0.53 (−0.49 to 1.54) | −1.25 (−2.39 to −0.12) | 0.019 |
TMT-A | −0.53 (−12.57 to +11.51) | +4.10 (−5.38 to +13.58) | 0.528 |
TMT-B | −3.18 (−22.47 to +16.12) | +9.15 (−14.41 to +32.71) | 0.400 |
COWA | +1.47 (−1.35 to +4.29) | +1.00 (−2.18 to +4.18) | 0.817 |
* Raw scores (HVLT-R), time (TMT-A/B), and word counts (COWA) were recorded, and all the tests were done in Mandarin version. Data are presented as means plus lower and upper limit of 95% CI.