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Serious treatment-related adverse events
| CTCAEa Category | Grade II | Grade III | Grade IV |
|---|---|---|---|
| Anorexia | 5 | 0 | 0 |
| Constipation | 4 | 0 | 0 |
| Diarrhea | 2 | 0 | 0 |
| Nausea/vomiting | 9 | 0 | 0 |
| Fatigue | 8 | 1 | 0 |
| Rash | 18 | 6 | 0 |
| Anemia | 18 | 3 | 0 |
| Leukopenia | 61 | 11 | 0 |
| Neutropenia | 31 | 7 | 0 |
| Thrombocytopenia | 15 | 5 | 2 |
| Infection | 11 | 3 | 0 |
| Thrombosis | 0 | 1 | 1 |
aCommon Terminology Criteria for Adverse Events (CTCAE) version 4.0.
