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. 2021 Mar 19;47(5):86. doi: 10.3892/ijmm.2021.4919

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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LXA4 inhibits TLR4 and MyD88 overexpression induced by PQ. Western blot analysis was performed to assess the protein levels of TLR4 and MyD88 in (A) rat lung tissues and (B) RAW264.7 cells. RT-qPCR analyses were performed to determine the gene levels of TLR4, MyD88, TRAM and TRIF in (C and E) rat lungs and (D and F) RAW264.7 cells. Data are presented as the means ± SD (n=10 in vivo, n=6 in vitro). ^#P<0.05 vs. the CON group. ^*P<0.05 vs. the PQ group. ns, not significant (P>0.05) vs. the CON group. ^##P>0.05 vs. the PQ group. LXA4, lipoxin A4; PQ, paraquat.